Infectious Diseases and HIV Conference

Ebola Virus Disease has emerged to be one of the deadliest infections due to Ebola virus, with a high proportion of mortality as well as the possibility of outbreaks on a large scale.

The session would cover pathogenesis, diagnostic difficulties, management of an outbreak, and the most recent treatment as well as prevention strategies which have been developed for EVD.

Pathogenesis and Transmission: Ebola virus is a Filoviridae family member, and it can be acquired through human contact, the route of which happens to be both through contact with infected animals as well as human-to-human by direct contact with an infected body fluid, contaminated objects, or even direct contact with infected people.

This session will focus on the pathogenesis of EVD how the virus targets various cell types for causing severe hemorrhagic fever and leading to multi-organ failure in most cases leading to death. Participants will be knowledgeable about the mechanisms that enable the virus to escape the immune system, and therefore the resultant cytokine storm contributing to the aggressiveness of the disease.

Clinical Presentation and Diagnosis: Early signs of EVD can be nonspecific-fever, headache, muscle aches, and fatigue. The more advanced stages lead to severe vomiting and diarrhea, internal or external bleeding, and shock. In this lecture, the various techniques of diagnosis of EVD will be discussed in the light of PCR-based tests, antigen-capture assays, and the use of point-of-care testing in resource-limited settings.

The differential diagnosis in areas where other infectious diseases are common will also be stressed. Outbreak Response and Public Health Strategies: The Ebola outbreaks pose grave challenges for those affected communities and health systems.

In this session, the elements of an effective outbreak response-including case identification, contact tracing, isolation, and infection control measures-will be discussed. Lessons learned from previous outbreaks-2014-2016-West Africa epidemic-reveal some of the ways in which these have guided current strategies to prevent and control future outbreaks.

Advances in Management and Therapy: There is a development in antiviral therapies, such as monoclonal antibodies, exemplified by mAb114 and REGN-EB3; the vs.-ZEBOV vaccine received its final approval for utility during outbreaks.

So this session will deal with how these treatments and vaccines did appear on the horizon to present improved mortality rates and stop disease transmission while further research goes on into new therapeutic choices.

Join us in a comprehensive session with leading experts as we delve into the very heart of Ebola virus disease: the line between knowing and not knowing its intricacies stretches into getting better response to the outbreak and informing treatment initiatives that save lives.